Anticoagulant 1,2,3,4,6-pentagalloyl-β-d-glucopyranose isolated from geranium (Pelargonium inquinans Ait)
MS Ji, XL Piao, YL Jin, RD Park - Archives of pharmacal research, 2005 - Springer
Abstract Geranium (Pelargonium inquinans Ait) leaves were extracted with 80% MeOH, and
partitioned into n-hexane, ethyl acetate, BuOH and H 2 O to isolate the anticoagulant
principles. The EtOAc fraction was found to be the most active, and was further purified using
silica and octadecylsilane column chromatography employing a bioassay-guided
fractionation method. The active compound was isolated and identified as 1, 2, 3, 4, 6-
pentagalloyl-β-d-glucopyranose (PGG)(compound I). The isolated anticoagulant significantly …
partitioned into n-hexane, ethyl acetate, BuOH and H 2 O to isolate the anticoagulant
principles. The EtOAc fraction was found to be the most active, and was further purified using
silica and octadecylsilane column chromatography employing a bioassay-guided
fractionation method. The active compound was isolated and identified as 1, 2, 3, 4, 6-
pentagalloyl-β-d-glucopyranose (PGG)(compound I). The isolated anticoagulant significantly …
Anticoagulant 1,2,3,4,6-pentagalloyl-β-D-glucopyranose isolated from geranium (Pelargonium inquinans Ait).
JMS Ji MyeongSim, PXL Piao XiangLan… - 2005 - cabidigitallibrary.org
Abstract Geranium (Pelargonium inquinans Ait) leaves were extracted with 80% MeOH, and
partitioned into n-hexane, ethyl acetate, BuOH and H2O to isolate the anticoagulant
principles. The EtOAc fraction was found to be the most active, and was further purified using
silica and octadecylsilane column chromatography employing a bioassay-guided
fractionation method. The active compound was isolated and identified as 1, 2, 3, 4, 6-
pentagalloyl-β-D-glucopyranose (PGG)(compound I). The isolated anticoagulant …
partitioned into n-hexane, ethyl acetate, BuOH and H2O to isolate the anticoagulant
principles. The EtOAc fraction was found to be the most active, and was further purified using
silica and octadecylsilane column chromatography employing a bioassay-guided
fractionation method. The active compound was isolated and identified as 1, 2, 3, 4, 6-
pentagalloyl-β-D-glucopyranose (PGG)(compound I). The isolated anticoagulant …
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